Resorbable Calcium Phosphate Osteoplastic Material for Bone Defect Repair

Osteoplastic material based on amorphous nanodispersed resorbable calcium hydroxyapatite in hyaluronate matrix for restoration and filling of bone tissue defects. The novelty of the material "Hyaluost" lies in the technology of synthesis of bioactive amorphous amorphous nanodispersed calcium hydroxyapatite, the only product of which is microgranulate with granule diameter: 0,5-1 microns. The microgranules consist of nanodispersed calcium hydroxyapatite particles of 5-10 nm in size and fibres loosely formed from the same particles incorporated in a polysaccharide matrix. Hyaluost" injected into the site of contact activates osteogenesis, increases the proliferative activity of osteoblasts and stimulates the processes of reparative osteogenesis at the site of injection, delays inflammatory processes in the bone wound. Hyaluost series preparations can be used as an osteoplastic material optimising bone tissue regeneration in dental surgery, as well as in traumatology and orthopaedics. "....